I just finished FMQ a good sized twin quilt (Holy Henrietta--you can see a pic in my current album) and had pretty good success with it. I tried Leah Day's idea of working in rows to keep me from getting into a tight spot. My quilting was on the large scale as I did not want it to be stiff when it was finished. I'd say the lines run anywhere from 1/2 to 2" apart in places. I started in the middle, worked down abot 4 to 6 inches and then up and to the left. That makes the "row". Then I started another "row" below and worked my way back to the middle. So on and so forth until that quarter was finished. I then went back to where I began and worked my way up the quilt row by row. That method worked really well for me.

I do not roll the quilt, but I make sure I have lots of surface area to hold the weight of the quilt. i play music as well, but just for background noise, not to quilt to. And, yes, I have done both STID and FMQ on the same quilt. Depending on the quilt, I'll go over the seams. It makes no difference. What matters is what YOU want to do with the quilt! The one I just finished was a log cabin, so there were LOTS AND LOTS of seams to quilt over. That block does not lend itself to anything other than a basic meander, so that's what I did. I like how it turned out.