I cut all pattern pieces first, then assemble. Borders and binding I cut last, I like to look at the top for a couple of days before making my mind up on those. I've also changed my posture/stance at the cutting board, which had made cutting easier by watching the Martelli "ergonomic" videos. Cut with the right side of my body in line with the rotary cutter and the edge of the ruler, much more satisfactory cuts and less tiring as well.