I wish you well with your wrist and hand pain. I've been suffering for close to two months now. X-rays showed only minimal arthritic changes and the doctor has me in an ACE splint and on Aleve for two weeks. I am 10 days into my treatment - and if it doesn't work I'm going to keep hand stitching and putting up with the pain! So there!! I was concerned about a ganglion but that is not the case, nor is mine carpal tunnel. I do believe the gloves help tremendously and highly recommend them.